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NUDT2

Gene

nudix hydrolase 2

HGNCHGNC:8049EnsemblENSG00000164978NCBI Gene318
Locus: gene with protein productLocation: 9p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAPAH1
View full nomenclature history (7)
Previous symbolsAPAH1
Previous namesnudix (nucleoside diphosphate linked moiety X)-type motif 2
Alias namesAp4A hydrolase 1, Ap4Aase, bis(5'-nucleosyl)-tetraphosphatase (asymmetrical), diadenosine tetraphosphatase, diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Polyneuropathy
Complex neurodevelopmental disorder
Melanoma
Neoplasms
Placental retention

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Nudix hydrolase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.