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OBSCN

Gene

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

HGNCHGNC:15719EnsemblENSG00000154358NCBI Gene84033
Locus: gene with protein productLocation: 1q42.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIAA1556 · UNC89 · KIAA1639 · ARHGEF30
View full nomenclature history (4)
Alias symbolsKIAA1556, UNC89, KIAA1639, ARHGEF30

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Atrial Fibrillation
Genetic Diseases, Inborn
Arrhythmogenic Right Ventricular Dysplasia
Rare familial disorder with hypertrophic cardiomyopathy
Musculoskeletal Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Fibronectin type III domain containingI-set domain containingDbl family Rho GEFsMyosin light chain kinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.