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PDE6B

Gene

phosphodiesterase 6B

HGNCHGNC:8786EnsemblENSG00000133256NCBI Gene5158
Locus: gene with protein productLocation: 4p16.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPDEB · CSNB3 · rd1 · RP40 · CSNBAD2
View full nomenclature history (8)
Previous symbolsPDEB
Alias symbolsCSNB3, rd1, RP40, CSNBAD2
Previous namesphosphodiesterase 6B, cGMP-specific, rod, beta
Alias namescongenital stationary night blindness 3, autosomal dominant, rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Retinitis Pigmentosa
Congenital stationary night blindness
Coronary Artery Disease
Stroke
Retinal Dystrophies

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Phosphodiesterases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.