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PDX1

Gene

pancreatic and duodenal homeobox 1

HGNCHGNC:6107EnsemblENSG00000139515NCBI Gene3651
Locus: gene with protein productLocation: 13q12.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asIPF1 · IDX-1 · STF-1 · PDX-1 · MODY4 · GSF · IUF-1
View full nomenclature history (12)
Previous symbolsIPF1
Alias symbolsIDX-1, STF-1, PDX-1, MODY4, GSF, IUF-1
Previous namesinsulin promoter factor 1, homeodomain transcription factor
Alias namesIslet/duodenum homeobox-1, somatostatin transcription factor 1, Glucose-sensitive factor, insulin upstream factor 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

MODY
Permanent neonatal diabetes mellitus
Diabetes Mellitus, Type 2
Scoliosis
Hypothyroidism
Exocrine pancreatic carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

HOXL subclass homeoboxes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.