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PHOX2A

Gene

paired like homeobox 2A

HGNCHGNC:691EnsemblENSG00000165462NCBI Gene401
Locus: gene with protein productLocation: 11q13.4

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asARIX · FEOM2 · PMX2A · CFEOM2
View full nomenclature history (7)
Previous symbolsARIX, FEOM2
Alias symbolsPMX2A, CFEOM2
Previous namesaristaless (Drosophila) homeobox, aristaless homeobox (Drosophila), fibrosis of extraocular muscles, congenital, 2, autosomal recessive, paired-like (aristaless) homeobox 2a, paired like homeobox 2a

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Congenital fibrosis of the extraocular muscles
Neurodegenerative Diseases
Parkinson's Disease
Alzheimer's Disease
Lysosomal Storage Diseases
Multiple Sclerosis
Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PRD class homeoboxes and pseudogenes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.