PIK3R2

Gene

phosphoinositide-3-kinase regulatory subunit 2

HGNCHGNC:8980 EnsemblENSG00000105647 NCBI Gene5296

Locus: gene with protein productLocation: 19p13.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asP85B · p85 · p85beta · p85-BETA

View full nomenclature history (6)

Alias symbolsP85B, p85, p85beta, p85-BETA

Previous namesphosphoinositide-3-kinase, regulatory subunit 2 (beta)

Alias namesphosphoinositide-3-kinase regulatory subunit beta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Megalencephaly - polymicrogyria - postaxial polydactyly - hydrocephalus

Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1

Neoplasms

overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes

Breast Neoplasms

Genetic Diseases, Inborn

Carcinoma, Non-Small-Cell Lung

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

SH2 domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.