PKD1

Gene

polycystin 1, transient receptor potential channel interacting

HGNCHGNC:9008 EnsemblENSG00000008710 NCBI Gene5310

Locus: gene with protein productLocation: 16p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPBP · Pc-1 · TRPP1

View full nomenclature history (6)

Alias symbolsPBP, Pc-1, TRPP1

Previous namespolycystic kidney disease 1 (autosomal dominant)

Alias namespolycystin 1, transient receptor potential cation channel, subfamily P, member 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Polycystic Kidney, Autosomal Dominant

Hypertension

Polycystic Kidney Diseases

Kidney Failure, Chronic

Renal Insufficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

C-type lectin domain containingMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.