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PLCB1

Gene

phospholipase C beta 1

HGNCHGNC:15917EnsemblENSG00000182621NCBI Gene23236
Locus: gene with protein productLocation: 20p12.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIAA0581 · PLC-I · PLC154
View full nomenclature history (5)
Alias symbolsKIAA0581, PLC-I, PLC154
Previous namesphospholipase C, beta 1 (phosphoinositide-specific)
Alias namesphosphoinositide phospholipase C

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypertension
Infantile spasms
Genetic developmental and epileptic encephalopathy
early-infantile DEE
Alcohol drinking

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PhospholipasesC2 domain containing phospholipases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.