PMAIP1

Gene

phorbol-12-myristate-13-acetate-induced protein 1

HGNCHGNC:9108 EnsemblENSG00000141682 NCBI Gene5366

Locus: gene with protein productLocation: 18q21.32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAPR · NOXA

View full nomenclature history (2)

Alias symbolsAPR, NOXA

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Leukemia, Lymphocytic, Chronic, B-Cell

Diabetes Mellitus, Type 2

Colitis, Ulcerative

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

BCL2 homology region 3 (BH3) only

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.