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POLD2

Gene

DNA polymerase delta 2, accessory subunit

HGNCHGNC:9176EnsemblENSG00000106628NCBI Gene5425
Locus: gene with protein productLocation: 7p13

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

DNA polymerase delta subunit 2P49005

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

View full nomenclature history (5)
Previous namespolymerase (DNA directed), delta 2, regulatory subunit (50kD), polymerase (DNA directed), delta 2, regulatory subunit 50kDa, polymerase (DNA) delta 2, accessory subunit
Alias namesPol delta B subunit (p50), DNA polymerase delta subunit p50

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Myeloid, Acute
Carcinoma, Non-Small-Cell Lung
Ovarian carcinoma
Neoplasms
Breast Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DNA polymerases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.