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POLD4

Gene

DNA polymerase delta 4, accessory subunit

HGNCHGNC:14106EnsemblENSG00000175482NCBI Gene57804
Locus: gene with protein productLocation: 11q13.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

DNA polymerase delta subunit 4Q9HCU8

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asp12 · POLDS
View full nomenclature history (5)
Alias symbolsp12, POLDS
Previous namespolymerase (DNA-directed), delta 4, accessory subunit, polymerase (DNA) delta 4, accessory subunit
Alias namesDNA polymerase delta smallest subunit p12

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Carcinoma, Non-Small-Cell Lung
Leukemia, Lymphocytic, Chronic, B-Cell
Exocrine pancreatic carcinoma
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DNA polymerases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.