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POLR2B

Gene

RNA polymerase II subunit B

HGNCHGNC:9188EnsemblENSG00000047315NCBI Gene5431
Locus: gene with protein productLocation: 4q12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRPB2
View full nomenclature history (2)
Alias symbolsRPB2
Previous namespolymerase (RNA) II (DNA directed) polypeptide B (140kD)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

HIV Infections
Dengue
Influenza, Human
Neurodegenerative Diseases
Atrial Fibrillation
Coronary Artery Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

RNA polymerase subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.