PPM1H

Gene

protein phosphatase, Mg2+/Mn2+ dependent 1H

HGNCHGNC:18583 EnsemblENSG00000111110 NCBI Gene57460

Locus: gene with protein productLocation: 12q14.1-q14.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asARHCL1 · KIAA1157 · FLJ13253 · NERPP-2C

View full nomenclature history (8)

Previous symbolsARHCL1

Alias symbolsKIAA1157, FLJ13253, NERPP-2C

Previous namesras homolog gene family, member C like 1, protein phosphatase 1H (PP2C domain containing), protein phosphatase, Mg2+/Mn2+ dependent, 1H

Alias namesneurite extension-related protein phosphatase related to PP2C

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Musculoskeletal Diseases

Iron Metabolism Disorders

Pre-Eclampsia

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatases, Mg2+/Mn2+ dependent

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.