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PPP2R2B

Gene

protein phosphatase 2 regulatory subunit Bbeta

HGNCHGNC:9305EnsemblENSG00000156475NCBI Gene5521
Locus: gene with protein productLocation: 5q32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSCA12 · PR55-BETA · PR52B · B55beta
View full nomenclature history (7)
Previous symbolsSCA12
Alias symbolsPR55-BETA, PR52B, B55beta
Previous namesspinocerebellar ataxia 12, protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
Alias namesPP2A subunit B isoform beta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Schizophrenia
Rheumatic Diseases
Placental abruption
Sialadenitis
Premature Birth
Gastrointestinal Neoplasms
Tinea

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

WD repeat domain containingProtein phosphatase 2 regulatory subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.