PRDM16

Gene

PR/SET domain 16

HGNCHGNC:14000 EnsemblENSG00000142611 NCBI Gene63976

Locus: gene with protein productLocation: 1p36.32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMEL1 · PFM13 · KIAA1675 · MGC166915 · KMT8F

View full nomenclature history (10)

Alias symbolsMEL1, PFM13, KIAA1675, MGC166915, KMT8F

Previous namesPR domain containing 16, PR domain 16

Alias namesMDS1/EVI1-like, PR-domain zinc finger protein 16, transcription factor MEL1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Left ventricular noncompaction

Familial isolated dilated cardiomyopathy

Coronary Artery Disease

Genetic Diseases, Inborn

Migraine Disorders

Glaucoma, Open-Angle

Cardiomyopathy, Dilated

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers C2H2-typePR/SET domain familyMicroRNA protein coding host genesPutative lysine methyltransferases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-11-07.

Open TargetsGene–disease associations from the Open Targets Platform.