PRIM2

Gene

DNA primase subunit 2

HGNCHGNC:9370 EnsemblENSG00000146143 NCBI Gene5558

Locus: gene with protein productLocation: 6p11.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

DNA primase large subunitP49643

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPRIM2A

View full nomenclature history (5)

Previous symbolsPRIM2A

Previous namesprimase, polypeptide 2A (58kD), primase, polypeptide 2A, 58kDa, primase, DNA, polypeptide 2 (58kDa), primase (DNA) subunit 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Myeloid, Acute

Carcinoma, Non-Small-Cell Lung

Ovarian carcinoma

Neoplasms

Breast Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.