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PRKCSH

Gene

PRKCSH beta subunit of glucosidase II

HGNCHGNC:9411EnsemblENSG00000130175NCBI Gene5589
Locus: gene with protein productLocation: 19p13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPLD1 · G19P1 · PCLD · VASAP-60 · GIIB · PKCSH · 80K-H · AGE-R2 · GIIbeta · GluIIbeta
View full nomenclature history (16)
Previous symbolsPLD1, G19P1, PCLD
Alias symbolsVASAP-60, GIIB, PKCSH, 80K-H, AGE-R2, GIIbeta, GluIIbeta
Previous namespolycystic liver disease, protein kinase C substrate 80K-H
Alias namesadvanced glycation end-product receptor 2, glucosidase II beta subunit, glucosidase 2 subunit beta, hepatocystin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Kartagener Syndrome
Liver Diseases
Genetic Diseases, Inborn
Gastrointestinal Diseases
COVID-19

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

EF-hand domain containingMRH domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-11-30.
Open TargetsGene–disease associations from the Open Targets Platform.