PRUNE2

Gene

prune homolog 2 with BCH domain

HGNCHGNC:25209 EnsemblENSG00000106772 NCBI Gene158471

Locus: gene with protein productLocation: 9q21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC9orf65 · BMCC1 · BNIPXL · A214N16.3 · bA214N16.3

View full nomenclature history (10)

Previous symbolsC9orf65

Alias symbolsBMCC1, BNIPXL, A214N16.3, bA214N16.3

Previous namesKIAA0367, chromosome 9 open reading frame 65, prune homolog 2 (Drosophila), prune homolog 2

Alias namesolfaxin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Dentures

Dental Caries

Sleep Apnea, Obstructive

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

BCH domain containingCRAL-TRIO lipid binding domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.