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PTCH1

Gene

patched 1

HGNCHGNC:9585EnsemblENSG00000185920NCBI Gene5727
Locus: gene with protein productLocation: 9q22.32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNBCCS · PTCH · BCNS · SLC65B1
View full nomenclature history (7)
Previous symbolsNBCCS, PTCH
Alias symbolsBCNS, SLC65B1
Previous namespatched (Drosophila) homolog, patched homolog (Drosophila), patched homolog 1 (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Basal cell carcinoma
Medulloblastoma
Inherited cancer-predisposing syndrome
Neoplastic Syndromes, Hereditary
Genetic Diseases, Inborn
Major depressive disorder
Intelligence

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Solute carrier family 65

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-02-05.
Open TargetsGene–disease associations from the Open Targets Platform.