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RC3H1

Gene

ring finger and CCCH-type domains 1

HGNCHGNC:29434EnsemblENSG00000135870NCBI Gene149041
Locus: gene with protein productLocation: 1q25.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRP5-1198E17.5 · RNF198 · KIAA2025 · roquin
View full nomenclature history (7)
Alias symbolsRP5-1198E17.5, RNF198, KIAA2025, roquin
Previous namesring finger and CCCH-type zinc finger domains 1
Alias namesKIAA2025 protein, roquin-1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hereditary antithrombin deficiency
Neurodegenerative Diseases
Lymphohistiocytosis, Hemophagocytic
Mental Disorders

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ring finger proteinsZinc fingers CCCH-type

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-11-24.
Open TargetsGene–disease associations from the Open Targets Platform.