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RELA

Gene

RELA proto-oncogene, NF-kB subunit

HGNCHGNC:9955EnsemblENSG00000173039NCBI Gene5970
Locus: gene with protein productLocation: 11q13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNFKB3 · p65
View full nomenclature history (4)
Previous symbolsNFKB3
Alias symbolsp65
Previous namesnuclear factor of kappa light polypeptide gene enhancer in B-cells 3, v-rel avian reticuloendotheliosis viral oncogene homolog A

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Alzheimer's Disease
Parkinson's Disease
Multiple Sclerosis
Immunologic Deficiency Syndromes
Severe Acute Respiratory Syndrome
Autoimmune disorder of central nervous system
Lysosomal Storage Diseases
Muscular Dystrophy, Duchenne

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

NF-kappa B complex subunitsIPT domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.