RORC

Gene

RAR related orphan receptor C

HGNCHGNC:10260 EnsemblENSG00000143365 NCBI Gene6097

Locus: gene with protein productLocation: 1q21.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Nuclear receptor ROR-gammaP51449

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRZRG · RORG · NR1F3 · TOR

View full nomenclature history (6)

Alias symbolsRZRG, RORG, NR1F3, TOR

Previous namesRAR-related orphan receptor C

Alias namesNuclear receptor ROR-gamma

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Asthma

Inflammatory Bowel Diseases

Colitis, Ulcerative

Hypothyroidism

Dermatitis, Atopic

Respiratory Tract Diseases

Rhinitis, Allergic

Psoriasis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

RAR related orphan receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-11-20.

Open TargetsGene–disease associations from the Open Targets Platform.