RPS6KA4

Gene

ribosomal protein S6 kinase A4

HGNCHGNC:10433 EnsemblENSG00000162302 NCBI Gene8986

Locus: gene with protein productLocation: 11q13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRSK-B · MSK2

View full nomenclature history (3)

Alias symbolsRSK-B, MSK2

Previous namesribosomal protein S6 kinase, 90kD, polypeptide 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Autoimmune disorder of central nervous system

Smoking initiation

Substance-Related Disorders

Skin Neoplasms

Biliary liver cirrhosis

Lupus Erythematosus, Systemic

Hypothyroidism

Actinic keratosis

Cutaneous melanoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MAPK activated protein kinasesMicroRNA protein coding host genesRibosomal protein S6 kinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.