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RSPO3

Gene

R-spondin 3

HGNCHGNC:20866EnsemblENSG00000146374NCBI Gene84870
Locus: gene with protein productLocation: 6q22.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTHSD2 · FLJ14440
View full nomenclature history (4)
Previous symbolsTHSD2
Alias symbolsFLJ14440
Previous namesthrombospondin, type I, domain containing 2, R-spondin 3 homolog (Xenopus laevis)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Fractures, Bone
Diabetes Mellitus, Type 2
Osteoporosis
Metabolic Syndrome
Smoking behavior
Endometriosis
Bone Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

R-spondin family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.