RTKN2

Gene

rhotekin 2

HGNCHGNC:19364 EnsemblENSG00000182010 NCBI Gene219790

Locus: gene with protein productLocation: 10q21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPLEKHK1 · Em:AC024597.2 · bA531F24.1 · FLJ39352

View full nomenclature history (5)

Previous symbolsPLEKHK1

Alias symbolsEm:AC024597.2, bA531F24.1, FLJ39352

Previous namespleckstrin homology domain containing, family K member 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypothyroidism

Arthritis, Rheumatoid

Graves' Disease

Thyroid Diseases

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Pleckstrin homology domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.