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RUNX1

Gene

RUNX family transcription factor 1

HGNCHGNC:10471EnsemblENSG00000159216NCBI Gene861
Locus: gene with protein productLocation: 21q22.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAML1 · CBFA2 · PEBP2A2 · AMLCR1
View full nomenclature history (8)
Previous symbolsAML1, CBFA2
Alias symbolsPEBP2A2, AMLCR1
Previous namesacute myeloid leukemia 1, runt-related transcription factor 1, runt related transcription factor 1
Alias namesaml1 oncogene

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Myeloid, Acute
Genetic Diseases, Inborn
Asthma
Alopecia
Arthritis, Rheumatoid
Myeloproliferative disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Runt-related transcription factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.