SCN4B

Gene

sodium voltage-gated channel beta subunit 4

HGNCHGNC:10592 EnsemblENSG00000177098 NCBI Gene6330

Locus: gene with protein productLocation: 11q23.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLQT10

View full nomenclature history (4)

Alias symbolsLQT10

Previous namessodium channel, voltage-gated, type IV, beta, sodium channel, voltage-gated, type IV, beta subunit, sodium channel, voltage gated, type IV beta subunit

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Atrial Fibrillation

Neurodegenerative Diseases

Sudden infant death syndrome

Cardiomyopathy, Dilated

Essential Tremor

Juvenile myoclonic epilepsy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

V-set domain containingSodium voltage-gated channel beta subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.