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Disease
Essential Tremor
Late-stage therapeutic developmentEmerging research
2
Publications
19
Clinical trials
1
Related conditions
2023
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Clinical trial2026-07-09Results posted · ClinicalTrials.gov
Clinical trial2026-07-09Status changed to Completed · ClinicalTrials.gov
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 4 clinical trials expected to report results, the earliest in Q4 2026.
Upcoming Milestones
- Q4 2026A Multicentre, Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate the Efficacy and Safety of BP1.4979 in Adult Patients With Essential Tremor
- Q1 2028Investigating the Role of Attention in Perceptual and Cognitive Consequences of Parkinson's Disease
- Q4 2028A Phase 2b Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Period to Evaluate the Efficacy and Safety of AGN-151607-DP (USAN: gemibotulinumtoxinA) for the Treatment of Upper Limb Essential Tremor in Adults
- Q4 2031Algorithms for Programming DBS Systems for ET
Major developments
Upcoming trial readoutHigh impact
Results expected Q4 20282026-06-29
Upcoming trial readoutImportant
Results expected Q1 20282026-05-05
Clinical MilestonesViewHide
Results expected
- 2026-06-29A Phase 2b Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Period to Evaluate the Efficacy and Safety of AGN-151607-DP (USAN: gemibotulinumtoxinA) for the Treatment of Upper Limb Essential Tremor in AdultsResults expected Q4 2028
- 2026-05-05Investigating the Role of Attention in Perceptual and Cognitive Consequences of Parkinson's DiseaseResults expected Q1 2028
- 2026-01-27Algorithms for Programming DBS Systems for ETResults expected Q4 2031
- 2025-12-16A Multicentre, Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate the Efficacy and Safety of BP1.4979 in Adult Patients With Essential TremorResults expected Q4 2026
Recently completed
Activity timeline5
- 2026-06-29ClinicalA Phase 2b Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Period to Evaluate the Efficacy and Safety of AGN-151607-DP (USAN: gemibotulinumtoxinA) for the Treatment of Upper Limb Essential Tremor in AdultsResults expected Q4 2028
- 2026-05-05ClinicalInvestigating the Role of Attention in Perceptual and Cognitive Consequences of Parkinson's DiseaseResults expected Q1 2028
- 2026-01-30ClinicalThe Swedish Essential Tremor (SWEET) Trial - A Multicentre Randomized Controlled Trial of Deep Brain Stimulation for Essential TremorPrimary completion
- 2026-01-27ClinicalAlgorithms for Programming DBS Systems for ETResults expected Q4 2031
- 2025-12-16ClinicalA Multicentre, Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate the Efficacy and Safety of BP1.4979 in Adult Patients With Essential TremorResults expected Q4 2026
Clinical trials
The current development programme across all trial phases.
Clinical programme
19
6
7
6
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
20132023
Most influential
Major themes3
- Deep Brain Stimulation1
- Essential Tremor1
- Parkinson Disease1
Leading journals2
- JAMA neurology1
- PLoS computational biology1
Leading researchers8
- Cagnan H1
- Chitnis S1
- Denison T1
- Denison-Smith A1
- Fleming JE1
- Lemmens O1
- Miocinovic S1
- Pont Sanchis I1
Affiliations (unnormalised)4
- Imperial College London1
- Institute of Biomedical Engineering1
- Nuffield Department of Clinical Neurosciences1
- University of Texas Southwestern Medical Center1
Related conditions
Diseases frequently studied alongside this one. Number shows shared papers.
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
A relatively common disorder characterized by a fairly specific pattern of tremors which are most prominent in the upper extremities and neck, inducing titubations of the head. The tremor is usually mild, but when severe may be disabling. An autosomal dominant pattern of inheritance may occur in some families (i.e., familial tremor). (Mov Disord 1988;13(1):5-10)
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.