ROBO2

Gene

roundabout guidance receptor 2

HGNCHGNC:10250 EnsemblENSG00000185008 NCBI Gene6092

Locus: gene with protein productLocation: 3p12.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIAA1568

View full nomenclature history (3)

Alias symbolsKIAA1568

Previous namesroundabout (axon guidance receptor, Drosophila) homolog 2, roundabout, axon guidance receptor, homolog 2 (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Diabetes Mellitus, Type 2

Smoking cessation

Colorectal adenocarcinoma

Smoking initiation

Essential Tremor

Obesity disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Fibronectin type III domain containingI-set domain containingIg-like cell adhesion molecule familyRoundabout guidance receptor family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.