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SCUBE2

Gene

signal peptide, CUB domain and EGF like domain containing 2

HGNCHGNC:30425EnsemblENSG00000175356NCBI Gene57758
Locus: gene with protein productLocation: 11p15.4

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCegf1 · Cegb1 · FLJ16792
View full nomenclature history (4)
Alias symbolsCegf1, Cegb1, FLJ16792
Previous namessignal peptide, CUB domain, EGF-like 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Prostate carcinoma
Anemia
Breast Neoplasms
Central Nervous System Neoplasms
Glioma
Myocardial Infarction
Osteogenesis Imperfecta
Hypocalcemic vitamin D-resistant rickets
Arthritis, Rheumatoid

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.