SDHAF2

Gene

succinate dehydrogenase complex assembly factor 2

HGNCHGNC:26034 EnsemblENSG00000167985 NCBI Gene54949

Locus: gene with protein productLocation: 11q12.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPGL2 · C11orf79 · FLJ20487 · SDH5

View full nomenclature history (6)

Previous symbolsPGL2, C11orf79

Alias symbolsFLJ20487, SDH5

Previous namesparaganglioma or familial glomus tumors 2, chromosome 11 open reading frame 79

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neoplastic Syndromes, Hereditary

Inherited cancer-predisposing syndrome

Paraganglioma

Carcinoma of liver and intrahepatic biliary tract

Carcinoma, Neuroendocrine

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Mitochondrial respiratory chain complex assembly factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.