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SELP

Gene

selectin P

HGNCHGNC:10721EnsemblENSG00000174175NCBI Gene6403
Locus: gene with protein productLocation: 1q24.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

P-selectinP16109

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asGRMP · CD62 · PSEL · PADGEM · GMP140 · CD62P · GMP-140
View full nomenclature history (13)
Previous symbolsGRMP
Alias symbolsCD62, PSEL, PADGEM, GMP140, CD62P, GMP-140
Previous namesselectin P (granule membrane protein 140kD, antigen CD62), selectin P (granule membrane protein 140kDa, antigen CD62)
Alias namesplatelet activation-dependent granule to external membrane protein, granule membrane protein 140kDa, P-selectin, antigen CD62

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Anemia, Sickle Cell
Atrial Fibrillation
Venous Thrombosis
Thrombophilia
Asthma
Pneumonia, Viral

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesSelectinsSushi domain containingC-type lectin domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-10-23.
Open TargetsGene–disease associations from the Open Targets Platform.