SH3GL1

Gene

SH3 domain containing GRB2 like 1, endophilin A2

HGNCHGNC:10830 EnsemblENSG00000141985 NCBI Gene6455

Locus: gene with protein productLocation: 19p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMGC111371 · SH3P8 · SH3D2B · CNSA1 · EEN

View full nomenclature history (13)

Alias symbolsMGC111371, SH3P8, SH3D2B, CNSA1, EEN

Previous namesSH3-domain GRB2-like 1, SH3 domain containing GRB2 like 1

Alias namesextra 11-19 leukemia fusion, fusion partner of MLL, SH3-containing Grb-2-like 1 protein, SH3-containing protein EEN, SH3 domain GRB2-like 1, endophilin A2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Listeriosis

Carcinoma of liver and intrahepatic biliary tract

Carcinoma, Ductal, Breast

Lymphoid neoplasm

Carcinoma, Non-Small-Cell Lung

Leukemia, Myeloid, Acute

Leukemia, Lymphocytic, Chronic, B-Cell

Multiple Myeloma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

N-BAR domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.