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SHFL

Gene

shiftless antiviral inhibitor of ribosomal frameshifting

HGNCHGNC:25649EnsemblENSG00000130813NCBI Gene55337
Locus: gene with protein productLocation: 19p13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC19orf66 · FLJ11286 · RyDEN · IRAV · SFL
View full nomenclature history (9)
Previous symbolsC19orf66
Alias symbolsFLJ11286, RyDEN, IRAV, SFL
Previous nameschromosome 19 open reading frame 66
Alias namesrepressor of yield of Dengue virus, interferon-regulated antiviral gene, shiftless

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Progressive familial intrahepatic cholestasis
Zika Virus Infection
Colorectal Neoplasms, Hereditary Nonpolyposis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.