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SHROOM2

Gene

shroom family member 2

HGNCHGNC:630EnsemblENSG00000146950NCBI Gene357
Locus: gene with protein productLocation: Xp22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAPXL
View full nomenclature history (4)
Previous symbolsAPXL
Previous namesapical protein, Xenopus laevis-like, apical protein-like (Xenopus laevis)
Alias namesProtein Shroom2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Prostate carcinoma
Colorectal adenocarcinoma
Prostatic Neoplasms
Meniere's Disease
Pemphigoid, Bullous
Neoplasms
Retinitis Pigmentosa

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PDZ domain containingShroom family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-10-05.
Open TargetsGene–disease associations from the Open Targets Platform.