SLC9A1

Gene

solute carrier family 9 member A1

HGNCHGNC:11071 EnsemblENSG00000090020 NCBI Gene6548

Locus: gene with protein productLocation: 1p36.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAPNH · NHE1 · NHE-1 · PPP1R143

View full nomenclature history (9)

Previous symbolsAPNH, NHE1, NHE-1

Alias symbolsPPP1R143

Previous namessolute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive), solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1, solute carrier family 9 (sodium/hydrogen exchanger), member 1

Alias namesprotein phosphatase 1, regulatory subunit 143, Sodium/hydrogen exchanger 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn

Tibial Fractures

Neoplasms

Glioma

Central Nervous System Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatase 1 regulatory subunitsSolute carrier family 9

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.