SMARCA4

Gene

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4

HGNCHGNC:11100 EnsemblENSG00000127616 NCBI Gene6597

Locus: gene with protein productLocation: 19p13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSNF2L4 · hSNF2b · BRG1 · BAF190 · SNF2 · SWI2 · SNF2-BETA · SNF2LB · FLJ39786

View full nomenclature history (19)

Previous symbolsSNF2L4

Alias symbolshSNF2b, BRG1, BAF190, SNF2, SWI2, SNF2-BETA, SNF2LB, FLJ39786

Previous namesSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

Alias namesSNF2-like 4, global transcription activator homologous sequence, sucrose nonfermenting-like 4, mitotic growth and transcription activator, BRM/SWI2-related gene 1, homeotic gene regulator, nuclear protein GRB1, brahma protein-like 1, ATP-dependent helicase SMARCA4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Rhabdoid Tumor

Medulloblastoma

Inherited cancer-predisposing syndrome

Neoplastic Syndromes, Hereditary

Adenocarcinoma of Lung

Carcinoma, Non-Small-Cell Lung

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

SNF2 related familyBromodomain containingBAF complex subunitsPBAF complex subunitsGBAF complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-09-19.

Open TargetsGene–disease associations from the Open Targets Platform.