SNRNP40

Gene

small nuclear ribonucleoprotein U5 subunit 40

HGNCHGNC:30857 EnsemblENSG00000060688 NCBI Gene9410

Locus: gene with protein productLocation: 1p35.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asWDR57 · PRPF8BP · PRP8BP · SPF38 · HPRP8BP

View full nomenclature history (8)

Previous symbolsWDR57

Alias symbolsPRPF8BP, PRP8BP, SPF38, HPRP8BP

Previous namesWD repeat domain 57 (U5 snRNP specific), small nuclear ribonucleoprotein 40kDa (U5), small nuclear ribonucleoprotein, U5 40kDa subunit

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Dengue

Lymphohistiocytosis, Hemophagocytic

Isolated agammaglobulinemia

Wiskott-Aldrich Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

WD repeat domain containingU5 small nuclear ribonucleoproteinSpliceosomal Bact complexSpliceosomal C complexSpliceosomal P complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.