ST3GAL3

Gene

ST3 beta-galactoside alpha-2,3-sialyltransferase 3

HGNCHGNC:10866 EnsemblENSG00000126091 NCBI Gene6487

Locus: gene with protein productLocation: 1p34.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSIAT6 · MRT12

View full nomenclature history (6)

Previous symbolsSIAT6, MRT12

Previous namessialyltransferase 6 (N-acetyllactosaminide alpha 2,3-sialyltransferase), mental retardation, non-syndromic, autosomal recessive, 12

Alias namesST3Gal III, N-acetyllactosaminide alpha-2,3-sialyltransferase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Infantile spasms

Autosomal recessive non-syndromic intellectual disability

Genetic developmental and epileptic encephalopathy

early-infantile DEE

COVID-19

Neurodegenerative Diseases

Genetic Diseases, Inborn

Attention Deficit Disorder with Hyperactivity

Severe Acute Respiratory Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

SialyltransferasesMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.