SYNDIG1

Gene

synapse differentiation inducing 1

HGNCHGNC:15885 EnsemblENSG00000101463 NCBI Gene79953

Locus: gene with protein productLocation: 20p11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC20orf39 · TMEM90B · FLJ14220 · IFITMD5 · DSPC2

View full nomenclature history (10)

Previous symbolsC20orf39, TMEM90B

Alias symbolsFLJ14220, IFITMD5, DSPC2

Previous nameschromosome 20 open reading frame 39, transmembrane protein 90B

Alias namesinterferon induced transmembrane protein domain containing 5, synapse differentiation induced gene 1, dispanin subfamily C member 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Diabetes Mellitus, Type 2

Gastrointestinal Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Dispanins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.