SYNJ1

Gene

synaptojanin 1

HGNCHGNC:11503 EnsemblENSG00000159082 NCBI Gene8867

Locus: gene with protein productLocation: 21q22.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asINPP5G · PARK20

View full nomenclature history (5)

Alias symbolsINPP5G, PARK20

Alias namessynaptic inositol 1,4,5-trisphosphate 5-phosphatase 1, inositol polyphosphate-5-phosphatase G, phosphoinositide 5-phosphatase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic developmental and epileptic encephalopathy

Genetic Diseases, Inborn

Undetermined early-onset epileptic encephalopathy

Alzheimer's Disease

Epilepsies, Myoclonic

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Phosphoinositide phosphatases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.