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TAL1

Gene

TAL bHLH transcription factor 1, erythroid differentiation factor

HGNCHGNC:11556EnsemblENSG00000162367NCBI Gene6886
Locus: gene with protein productLocation: 1p33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTCL5 · SCL · bHLHa17
View full nomenclature history (4)
Previous symbolsTCL5
Alias symbolsSCL, bHLHa17
Previous namesT-cell acute lymphocytic leukemia 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Dengue
peripheral T-cell lymphoma, not otherwise specified
Lymphoma, T-Cell, Cutaneous
Diabetes Mellitus, Type 2
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Carcinoma, Hepatocellular
Carcinoma, Non-Small-Cell Lung
Melanoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Basic helix-loop-helix proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.