TBL1XR1

Gene

TBL1X/Y related 1

HGNCHGNC:29529 EnsemblENSG00000177565 NCBI Gene79718

Locus: gene with protein productLocation: 3q26.32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asIRA1 · FLJ12894 · TBLR1 · C21 · DC42

View full nomenclature history (10)

Alias symbolsIRA1, FLJ12894, TBLR1, C21, DC42

Previous namestransducin (beta)-like 1X-linked receptor 1, transducin beta like 1 X-linked receptor 1, TBL1X receptor 1

Alias namesF-box-like/WD repeat-containing protein TBL1XR1, TBL1-related protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lymphoma, Large B-Cell, Diffuse

Neurodegenerative Diseases

Asthma

Genetic Diseases, Inborn

Complex neurodevelopmental disorder

Respiratory Tract Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

WD repeat domain containingNCoR/SMRT transcriptional repression complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.