TFF1

Gene

trefoil factor 1

HGNCHGNC:11755 EnsemblENSG00000160182 NCBI Gene7031

Locus: gene with protein productLocation: 21q22.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asBCEI · D21S21 · HPS2 · pS2 · pNR-2 · HP1.A

View full nomenclature history (7)

Previous symbolsBCEI

Alias symbolsD21S21, HPS2, pS2, pNR-2, HP1.A

Previous namesbreast cancer, estrogen-inducible sequence expressed in

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Exocrine pancreatic carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.