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TGFB1

Gene

transforming growth factor beta 1

HGNCHGNC:11766EnsemblENSG00000105329NCBI Gene7040
Locus: gene with protein productLocation: 19q13.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Transforming growth factor beta-1 proproteinP01137

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTGFB · DPD1 · CED · TGFbeta
View full nomenclature history (8)
Previous symbolsTGFB, DPD1
Alias symbolsCED, TGFbeta
Previous namestransforming growth factor, beta 1
Alias namesCamurati-Engelmann disease, prepro-transforming growth factor beta-1, Diaphyseal dysplasia 1, progressive

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Myelodysplastic syndrome
Anemia
Neoplasms
beta-Thalassemia
Cystic Fibrosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Transforming growth factor beta family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.