TIA1

Gene

TIA1 cytotoxic granule associated RNA binding protein

HGNCHGNC:11802 EnsemblENSG00000116001 NCBI Gene7072

Locus: gene with protein productLocation: 2p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTIA-1

View full nomenclature history (4)

Alias symbolsTIA-1

Previous namesTIA1 cytotoxic granule-associated RNA-binding protein

Alias namesT-cell-restricted intracellular antigen-1, nucleolysin TIA-1 isoform p40

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn

Neoplasms

Amyotrophic Lateral Sclerosis

Tauopathies

Carcinoma, Hepatocellular

Esophageal Squamous Cell Carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

RNA binding motif containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.