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TNFSF11

Gene

TNF superfamily member 11

HGNCHGNC:11926EnsemblENSG00000120659NCBI Gene8600
Locus: gene with protein productLocation: 13q14.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTRANCE · RANKL · OPGL · ODF · CD254
View full nomenclature history (6)
Alias symbolsTRANCE, RANKL, OPGL, ODF, CD254
Previous namestumor necrosis factor (ligand) superfamily, member 11

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Osteoporosis
Osteoporosis, Postmenopausal
Bone Diseases
Multiple Myeloma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesTumor necrosis factor superfamily

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-01-15.
Open TargetsGene–disease associations from the Open Targets Platform.