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TNS2

Gene

tensin 2

HGNCHGNC:19737EnsemblENSG00000111077NCBI Gene23371
Locus: gene with protein productLocation: 12q13.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTENC1 · KIAA1075 · C1-TEN
View full nomenclature history (5)
Previous symbolsTENC1
Alias symbolsKIAA1075, C1-TEN
Previous namestensin like C1 domain-containing phosphatase, tensin like C1 domain containing phosphatase (tensin 2)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Nephrotic Syndrome
Hypertension
Essential Hypertension
Hypertension, Pregnancy-Induced
Pre-Eclampsia
Osteoarthritis, Knee

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

SH2 domain containingC2 tensin-type domain containingPTEN protein phosphatasesMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.