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TREML2

Gene

triggering receptor expressed on myeloid cells like 2

HGNCHGNC:21092EnsemblENSG00000112195NCBI Gene79865
Locus: gene with protein productLocation: 6p21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC6orf76 · FLJ13693 · TLT2 · dJ238O23.1
View full nomenclature history (7)
Previous symbolsC6orf76
Alias symbolsFLJ13693, TLT2, dJ238O23.1
Previous nameschromosome 6 open reading frame 76, triggering receptor expressed on myeloid cells-like 2
Alias namesTREM-like transcript 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Alzheimer's Disease
Lewy Body Disease
Diabetes Mellitus, Type 2
Leukemia, Myeloid, Acute
Infections
COVID-19
Glioblastoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

V-set domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.