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TTC21A

Gene

tetratricopeptide repeat domain 21A

HGNCHGNC:30761EnsemblENSG00000168026NCBI Gene199223
Locus: gene with protein productLocation: 3p22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSTI2 · IFT139A · Thm2
View full nomenclature history (4)
Alias symbolsSTI2, IFT139A, Thm2
Alias namesStress-inducible protein 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Spermatogenic failure
Non-syndromic male infertility due to sperm motility disorder
Hypotension
Skin Diseases
Colorectal Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Tetratricopeptide repeat domain containingMicroRNA protein coding host genesIFT-A complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.